Millions with kidney failure need a transplant – XVIVO gives them new hope

Globally, 5–7 million people live with end-stage kidney disease. To them, each day represents a struggle to survive. Their kidneys simply can’t perform tasks like removing waste, salt and extra water to prevent these from accumulating in the body.

Put simply, these people have two treatment alternatives.

One is dialysis, where a machine filters and cleanses the blood. But dialysis must be performed several times each week and every treatment is a long and tiresome process. A better alternative, both for patients and society, is a kidney transplant. Compared to a patient undergoing dialysis, a transplant recipient can expect a longer life.

A patient on dialysis typically has a renal function of 10–15 per cent or less, whereas a donated kidney will allow the recipient a better everyday quality of life, free from the need of dialysis.

Unfortunately, there are not nearly enough kidneys available for transplantation. Only a small fraction of deaths allows for organs to be donated, and hospitals discard one in three donated kidneys.

XVIVO works to increase the availability of kidneys – using an innovative method with cold oxygenated machine perfusion. The ground-breaking transport solution, XVIVO’s Kidney Assist Transport, preserves the kidney during transport by restoring the flow and adding oxygen and nutrients to the organs.

Put together, XVIVO’s technology aims to reduce the risk of kidney failure and organ rejection while improving organ function.*

For the individual patient, this enriches and extends their lives. For XVIVO, it means fulfilling a vision stating that nobody should die waiting for a new organ.


*For more details on the trial investigating the benefits of oxygenated machine perfusion, see: Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, doubleblind, paired, phase 3 trial. Lancet 2020; 396: 1653–62

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